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PharmaInsight

Mefenamic acid vs Methotrexate

National NHS prescribing compared (Prescription Cost Analysis)
Data updated March 2026

Methotrexate was dispensed 5.8× as often as Mefenamic acid in March 2026 — 190,005 items versus 32,622 in England.

32,622items

Mefenamic acid · March 2026

NHSBSA Prescription Cost Analysis

190,005items

Methotrexate · March 2026

NHSBSA Prescription Cost Analysis

Figure 1. Mefenamic acid versus Methotrexate: national items dispensed by month

▬ Mefenamic acid   ·   ╌ Methotrexate

Methotrexate 32,622

Source: NHSBSA Prescription Cost Analysis, to March 2026

Mefenamic acid versus Methotrexate, March 2026
Measure Mefenamic acid Methotrexate
Items, March 2026 32,622 190,005
Items, last 12 months 350,746 2,236,642
Net ingredient cost, March 2026 £922,854 £2,295,534

See the full profile for Mefenamic acid or Methotrexate.