Methotrexate vs Hydroxycarbamide
National NHS prescribing compared (Prescription Cost Analysis)
Hydroxycarbamide was dispensed 2.3× as often as Methotrexate in May 2026 — 7,469 items versus 3,225 in England.
3,225items
Methotrexate · May 2026
NHSBSA Prescription Cost Analysis
7,469items
Hydroxycarbamide · May 2026
NHSBSA Prescription Cost Analysis
Figure 1. Methotrexate versus Hydroxycarbamide: national items dispensed by month
▬ Methotrexate · ╌ Hydroxycarbamide
Source: NHSBSA Prescription Cost Analysis, to May 2026
| Measure | Methotrexate | Hydroxycarbamide |
|---|---|---|
| Items, May 2026 | 3,225 | 7,469 |
| Items, last 12 months | 40,622 | 93,745 |
| Net ingredient cost, May 2026 | £213,236 | £83,821 |
See the full profile for Methotrexate or Hydroxycarbamide.