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PharmaInsight

Methotrexate vs Hydroxycarbamide

National NHS prescribing compared (Prescription Cost Analysis)
Data updated March 2026

Hydroxycarbamide was dispensed 2.4× as often as Methotrexate in March 2026 — 7,984 items versus 3,350 in England.

3,350items

Methotrexate · March 2026

NHSBSA Prescription Cost Analysis

7,984items

Hydroxycarbamide · March 2026

NHSBSA Prescription Cost Analysis

Figure 1. Methotrexate versus Hydroxycarbamide: national items dispensed by month

▬ Methotrexate   ·   ╌ Hydroxycarbamide

Hydroxycarbamide 3,350

Source: NHSBSA Prescription Cost Analysis, to March 2026

Methotrexate versus Hydroxycarbamide, March 2026
Measure Methotrexate Hydroxycarbamide
Items, March 2026 3,350 7,984
Items, last 12 months 41,023 93,903
Net ingredient cost, March 2026 £219,960 £102,840

See the full profile for Methotrexate or Hydroxycarbamide.