Medicines
Malignant Disease and Immunosuppression
Cytotoxic drugs
Methotrexate

Methotrexate

Malignant Disease and Immunosuppression Cytotoxic drugs BNF 0801030P0

Data updated April 2026 Download CSV

Methotrexate was ranked 673rd of 1,792 medicines by items in April 2026, with 3,311 items, down 2.5% on a year earlier.

3,311items -2.5%

Dispensed in April 2026

37,397items

Rolling 12 months

£218,895

Net ingredient cost · April 2026

Figure 1. Methotrexate: national items dispensed by month

Source: NHSBSA Prescription Cost Analysis, to April 2026

Download CSV

Embed this chart

<iframe src="https://pharmainsight.co.uk/embed/medicines/methotrexate-0801030p0" width="100%" height="280" style="border:0" loading="lazy" title="Methotrexate: NHS prescribing in England — PharmaInsight"></iframe>

At a glance

Therapeutic class Cytotoxic drugs
Presentations 15 shown
Average cost / item £66.11
Year on year Down 2.5% on a year earlier

What this is

Net ingredient cost is the list price before discounts and dispensing fees, not what the NHS finally pays.

Top presentations, April 2026

The individual products dispensed under Methotrexate this month.

Presentations of Methotrexate, April 2026
Presentation	BNF code	Items	Net ingredient cost
Nordimet 20mg/0.8ml solution for injection pre-filled pens	0801030P0BFAFFS	933	£64,609
Nordimet 15mg/0.6ml solution for injection pre-filled pens	0801030P0BFADFQ	735	£46,207
Nordimet 25mg/1ml solution for injection pre-filled pens	0801030P0BFAHFU	536	£38,056
Nordimet 10mg/0.4ml solution for injection pre-filled pens	0801030P0BFABFN	281	£16,483
Nordimet 12.5mg/0.5ml solution for injection pre-filled pens	0801030P0BFACFP	184	£12,058
Nordimet 17.5mg/0.7ml solution for injection pre-filled pens	0801030P0BFAEFR	183	£12,332
Nordimet 22.5mg/0.9ml solution for injection pre-filled pens	0801030P0BFAGFT	113	£7,790
Nordimet 7.5mg/0.3ml solution for injection pre-filled pens	0801030P0BFAAFM	99	£5,388
Zlatal 25mg/1ml solution for injection pre-filled syringes	0801030P0BEACFG	59	£4,360
Zlatal 15mg/0.6ml solution for injection pre-filled syringes	0801030P0BEAGFK	57	£3,596
Zlatal 20mg/0.8ml solution for injection pre-filled syringes	0801030P0BEAAFE	52	£3,276
Zlatal 10mg/0.4ml solution for injection pre-filled syringes	0801030P0BEADFH	23	£1,267
Zlatal 7.5mg/0.3ml inj pre-filled syringes	0801030P0BEAEFI	16	£882
Zlatal 22.5mg/0.9ml inj pre-filled syringes	0801030P0BEABFF	15	£1,129
Zlatal 17.5mg/0.7ml inj pre-filled syringes	0801030P0BEAHFL	14	£882

Source: NHSBSA Prescription Cost Analysis · to April 2026 OGL v3.0

Where Methotrexate is dispensed

The regions and dispensing practices with the highest Methotrexate volumes.

Top regions

Top dispensing practices

Regional volumes from NHSBSA Prescription Cost Analysis; practice volumes from NHS dispensing data.

Compare Methotrexate with

Other medicines in the same BNF section, by prescribing volume.

Methotrexate vs Fluorouracil (Antimetabolites) Methotrexate vs Hydroxycarbamide Methotrexate vs Mercaptopurine Methotrexate vs Calcium folinate Methotrexate vs Cyclophosphamide