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PharmaInsight

Methotrexate vs Tioguanine

National NHS prescribing compared (Prescription Cost Analysis)
Data updated March 2026

Methotrexate was dispensed 1,116.7× as often as Tioguanine in March 2026 — 3,350 items versus 3 in England.

3,350items

Methotrexate · March 2026

NHSBSA Prescription Cost Analysis

3items

Tioguanine · March 2026

NHSBSA Prescription Cost Analysis

Figure 1. Methotrexate versus Tioguanine: national items dispensed by month

▬ Methotrexate   ·   ╌ Tioguanine

Tioguanine 3,350

Source: NHSBSA Prescription Cost Analysis, to March 2026

Methotrexate versus Tioguanine, March 2026
Measure Methotrexate Tioguanine
Items, March 2026 3,350 3
Items, last 12 months 41,023 19
Net ingredient cost, March 2026 £219,960 £92

See the full profile for Methotrexate or Tioguanine.