Skip to content
PharmaInsight

Methotrexate vs Febuxostat

National NHS prescribing compared (Prescription Cost Analysis)
Data updated March 2026

Methotrexate was dispensed 9.7× as often as Febuxostat in March 2026 — 190,005 items versus 19,643 in England.

190,005items

Methotrexate · March 2026

NHSBSA Prescription Cost Analysis

19,643items

Febuxostat · March 2026

NHSBSA Prescription Cost Analysis

Figure 1. Methotrexate versus Febuxostat: national items dispensed by month

▬ Methotrexate   ·   ╌ Febuxostat

Febuxostat 190,005

Source: NHSBSA Prescription Cost Analysis, to March 2026

Methotrexate versus Febuxostat, March 2026
Measure Methotrexate Febuxostat
Items, March 2026 190,005 19,643
Items, last 12 months 2,236,642 227,086
Net ingredient cost, March 2026 £2,295,534 £104,382

See the full profile for Methotrexate or Febuxostat.