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Sertraline hydrochloride vs Venlafaxine

National NHS prescribing compared (Prescription Cost Analysis)
Data updated March 2026

Sertraline hydrochloride was dispensed 4.0× as often as Venlafaxine in March 2026 — 2,236,611 items versus 554,493 in England.

2,236,611items

Sertraline hydrochloride · March 2026

NHSBSA Prescription Cost Analysis

554,493items

Venlafaxine · March 2026

NHSBSA Prescription Cost Analysis

Figure 1. Sertraline hydrochloride versus Venlafaxine: national items dispensed by month

▬ Sertraline hydrochloride   ·   ╌ Venlafaxine

Venlafaxine 2,236,611

Source: NHSBSA Prescription Cost Analysis, to March 2026

Sertraline hydrochloride versus Venlafaxine, March 2026
Measure Sertraline hydrochloride Venlafaxine
Items, March 2026 2,236,611 554,493
Items, last 12 months 25,770,008 6,430,122
Net ingredient cost, March 2026 £3,964,693 £5,383,757

See the full profile for Sertraline hydrochloride or Venlafaxine.