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Independent analysis of NHS open data
PharmaInsight

Sertraline hydrochloride

Central Nervous System Antidepressant drugs BNF 0403030Q0
Data updated April 2026 Download CSV

Sertraline hydrochloride was the 10th most-dispensed medicine in England in April 2026, with 2,190,016 items, up 5.9% on a year earlier.

2,190,016items +5.9%

Dispensed in April 2026

23,749,909items

Rolling 12 months

£3,713,543

Net ingredient cost · April 2026

Figure 1. Sertraline hydrochloride: national items dispensed by month

0 1.1m 2.3m Jan 2021 Nov 2021 Sep 2022 Jul 2023 May 2024 Mar 2025 Apr 2026 2,190,016 Jan 2021: 1.6m Feb 2021: 1.5m Mar 2021: 1.7m Apr 2021: 1.7m May 2021: 1.6m Jun 2021: 1.7m Jul 2021: 1.7m Aug 2021: 1.7m Sep 2021: 1.7m Oct 2021: 1.7m Nov 2021: 1.8m Dec 2021: 1.8m Jan 2022: 1.8m Feb 2022: 1.7m Mar 2022: 1.9m Apr 2022: 1.7m May 2022: 1.8m Jun 2022: 1.8m Jul 2022: 1.8m Aug 2022: 1.8m Sep 2022: 1.8m Oct 2022: 1.8m Nov 2022: 1.9m Dec 2022: 1.9m Jan 2023: 1.9m Feb 2023: 1.8m Mar 2023: 2m Apr 2023: 1.8m May 2023: 1.9m Jun 2023: 2m Jul 2023: 1.9m Aug 2023: 2m Sep 2023: 1.9m Oct 2023: 2m Nov 2023: 2m Dec 2023: 2m Jan 2024: 2.1m Feb 2024: 1.9m Mar 2024: 2m Apr 2024: 2m May 2024: 2.1m Jun 2024: 1.9m Jul 2024: 2.1m Aug 2024: 2m Sep 2024: 2m Oct 2024: 2.1m Nov 2024: 2m Dec 2024: 2.1m Jan 2025: 2.2m Feb 2025: 1.9m Mar 2025: 2.1m Apr 2025: 2.1m May 2025: 2.1m Jun 2025: 2.1m Jul 2025: 2.2m Aug 2025: 2m Sep 2025: 2.2m Oct 2025: 2.2m Nov 2025: 2.1m Dec 2025: 2.3m Jan 2026: 2.2m Feb 2026: 2m Mar 2026: 2.2m Apr 2026: 2.2m

Source: NHSBSA Prescription Cost Analysis, to April 2026

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At a glance

  • Therapeutic class Antidepressant drugs
  • Presentations 15 shown
  • Average cost / item £1.70
  • Year on year Up 5.9% on a year earlier
What this is
Net ingredient cost is the list price before discounts and dispensing fees, not what the NHS finally pays.

Top presentations, April 2026

The individual products dispensed under Sertraline hydrochloride this month.

Presentations of Sertraline hydrochloride, April 2026
Presentation BNF code Items Net ingredient cost
Sertraline 50mg tablets 0403030Q0AAAAAA 1,126,917 £1,068,539
Sertraline 100mg tablets 0403030Q0AAABAB 980,264 £1,175,361
Sertraline 25mg tablets 0403030Q0AAAZAZ 64,673 £382,573
Sertraline 150mg tablets 0403030Q0AABABA 8,810 £152,713
Sertraline 200mg tablets 0403030Q0AABBBB 5,043 £113,122
Sertraline 50mg/5ml oral suspension sugar free 0403030Q0AABDBD 1,063 £351,270
Sertraline 100mg/5ml concentrate for oral soln sugar free 0403030Q0AABCBC 943 £179,237
Lustral 50mg tablets 0403030Q0BBAAAA 896 £28,358
Lustral 100mg tablets 0403030Q0BBABAB 610 £23,288
Sertraline 50mg/5ml oral suspension 0403030Q0AAAQAQ 349 £154,105
Contulen 50mg tablets 0403030Q0BCAAAA 170 £3,210
Contulen 100mg tablets 0403030Q0BCABAB 118 £3,660
Sertraline 100mg/5ml oral suspension 0403030Q0AAARAR 82 £42,135
Sertraline 25mg/5ml oral suspension 0403030Q0AAAXAX 41 £23,673
Sertraline 50mg/5ml oral solution 0403030Q0AAAVAV 33 £9,861

Source: NHSBSA Prescription Cost Analysis · to April 2026 OGL v3.0

Where Sertraline hydrochloride is dispensed

The regions and dispensing practices with the highest Sertraline hydrochloride volumes.

Regional volumes from NHSBSA Prescription Cost Analysis; practice volumes from NHS dispensing data.

Compare Sertraline hydrochloride with

Other medicines in the same BNF section, by prescribing volume.