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Independent analysis of NHS open data
PharmaInsight

Tofacitinib vs Methotrexate

National NHS prescribing compared (Prescription Cost Analysis)
Data updated March 2026

Methotrexate was dispensed 182,888.0× as often as Tofacitinib in March 2026 — 182,888 items versus 1 in England.

1items

Tofacitinib · March 2026

NHSBSA Prescription Cost Analysis

182,888items

Methotrexate · March 2026

NHSBSA Prescription Cost Analysis

Figure 1. Tofacitinib versus Methotrexate: national items dispensed by month

▬ Tofacitinib   ·   ╌ Methotrexate

0 99k 198k Jan 2021 Sep 2021 Dec 2021 Dec 2022 Jan 2024 Mar 2026 Methotrexate 1 Jan 2021: 2 Aug 2021: 1 Sep 2021: 3 Nov 2021: 1 Dec 2021: 1 Mar 2022: 1 Dec 2022: 1 Dec 2023: 1 Jan 2024: 1 Apr 2025: 1 May 2025: 1 Mar 2026: 1

Source: NHSBSA Prescription Cost Analysis, to March 2026

Tofacitinib versus Methotrexate, March 2026
Measure Tofacitinib Methotrexate
Items, March 2026 1 182,888
Items, last 12 months 15 2,236,227
Net ingredient cost, March 2026 £12 £2,247,752

See the full profile for Tofacitinib or Methotrexate.