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PharmaInsight

Upadacitinib vs Methotrexate

National NHS prescribing compared (Prescription Cost Analysis)
Data updated January 2026

Methotrexate was dispensed 190,005.0× as often as Upadacitinib in January 2026 — 190,005 items versus 1 in England.

1items

Upadacitinib · January 2026

NHSBSA Prescription Cost Analysis

190,005items

Methotrexate · January 2026

NHSBSA Prescription Cost Analysis

Figure 1. Upadacitinib versus Methotrexate: national items dispensed by month

▬ Upadacitinib   ·   ╌ Methotrexate

Methotrexate 1

Source: NHSBSA Prescription Cost Analysis, to January 2026

Upadacitinib versus Methotrexate, January 2026
Measure Upadacitinib Methotrexate
Items, January 2026 1 190,005
Items, last 12 months 22 2,236,642
Net ingredient cost, January 2026 £806 £2,295,534

See the full profile for Upadacitinib or Methotrexate.