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Independent analysis of NHS open data
PharmaInsight

Dornase alfa

Respiratory System Mucolytics BNF 0307000K0
Data updated May 2026 Download CSV

Dornase alfa was ranked 1103rd of 1,792 medicines by items in May 2026, with 228 items, down 24.5% on a year earlier.

228items -24.5%

Dispensed in May 2026

3,074items

Rolling 12 months

£132,977

Net ingredient cost · May 2026

Figure 1. Dornase alfa: national items dispensed by month

0 322.5 645 Jan 2021 Nov 2021 Sep 2022 Jul 2023 May 2024 Mar 2025 May 2026 228 Jan 2021: 645 Feb 2021: 592 Mar 2021: 617 Apr 2021: 577 May 2021: 561 Jun 2021: 559 Jul 2021: 556 Aug 2021: 497 Sep 2021: 573 Oct 2021: 509 Nov 2021: 520 Dec 2021: 524 Jan 2022: 526 Feb 2022: 465 Mar 2022: 504 Apr 2022: 421 May 2022: 448 Jun 2022: 430 Jul 2022: 427 Aug 2022: 432 Sep 2022: 407 Oct 2022: 417 Nov 2022: 405 Dec 2022: 429 Jan 2023: 402 Feb 2023: 342 Mar 2023: 395 Apr 2023: 329 May 2023: 348 Jun 2023: 371 Jul 2023: 356 Aug 2023: 338 Sep 2023: 330 Oct 2023: 313 Nov 2023: 331 Dec 2023: 321 Jan 2024: 305 Feb 2024: 306 Mar 2024: 325 Apr 2024: 308 May 2024: 326 Jun 2024: 289 Jul 2024: 337 Aug 2024: 283 Sep 2024: 288 Oct 2024: 345 Nov 2024: 296 Dec 2024: 324 Jan 2025: 293 Feb 2025: 268 Mar 2025: 271 Apr 2025: 255 May 2025: 302 Jun 2025: 271 Jul 2025: 279 Aug 2025: 247 Sep 2025: 266 Oct 2025: 278 Nov 2025: 234 Dec 2025: 301 Jan 2026: 258 Feb 2026: 223 Mar 2026: 239 Apr 2026: 250 May 2026: 228

Source: NHSBSA Prescription Cost Analysis, to May 2026

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At a glance

  • Therapeutic class Mucolytics
  • Presentations 1 shown
  • Average cost / item £583.23
  • Year on year Down 24.5% on a year earlier
What this is
Net ingredient cost is the list price before discounts and dispensing fees, not what the NHS finally pays.

Top presentations, May 2026

The individual products dispensed under Dornase alfa this month.

Presentations of Dornase alfa, May 2026
Presentation BNF code Items Net ingredient cost
Pulmozyme 2.5mg nebuliser liquid 2.5ml ampoules 0307000K0BBAAAA 228 £132,977

Source: NHSBSA Prescription Cost Analysis · to May 2026 OGL v3.0

Where Dornase alfa is dispensed

The regions and dispensing practices with the highest Dornase alfa volumes.

Regional volumes from NHSBSA Prescription Cost Analysis; practice volumes from NHS dispensing data.

In NHS hospitals

Dornase alfa is also used in NHS secondary care. See the indicative hospital cost, monthly trend and the trusts using it most on the hospital medicines page.

Compare Dornase alfa with

Other medicines in the same BNF section, by prescribing volume.