Medicines
Central Nervous System
Antidepressant drugs
Duloxetine hydrochloride

Duloxetine hydrochloride

Central Nervous System Antidepressant drugs BNF 0403040Y0

Data updated April 2026 Download CSV

Duloxetine hydrochloride was ranked 51st of 1,792 medicines by items in April 2026, with 455,024 items, up 13.4% on a year earlier.

455,024items +13.4%

Dispensed in April 2026

4,787,855items

Rolling 12 months

£1,501,275

Net ingredient cost · April 2026

Figure 1. Duloxetine hydrochloride: national items dispensed by month

Source: NHSBSA Prescription Cost Analysis, to April 2026

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At a glance

Therapeutic class Antidepressant drugs
Presentations 10 shown
Average cost / item £3.30
Year on year Up 13.4% on a year earlier

What this is

Net ingredient cost is the list price before discounts and dispensing fees, not what the NHS finally pays.

Top presentations, April 2026

The individual products dispensed under Duloxetine hydrochloride this month.

Presentations of Duloxetine hydrochloride, April 2026
Presentation	BNF code	Items	Net ingredient cost
Duloxetine 60mg gastro-resistant capsules	0403040Y0AAABAB	264,276	£573,771
Duloxetine 30mg gastro-resistant capsules	0403040Y0AAAAAA	172,226	£314,705
Duloxetine 90mg gastro-resistant capsules	0403040Y0AAACAC	12,026	£388,579
Duloxetine 120mg gastro-resistant capsules	0403040Y0AAADAD	5,920	£216,734
Depalta 60mg gastro-resistant capsules	0403040Y0BDABAB	309	£1,402
Cymbalta 60mg gastro-resistant capsules	0403040Y0BBABAB	95	£3,652
Depalta 30mg gastro-resistant capsules	0403040Y0BDAAAA	117	£415
Cymbalta 30mg gastro-resistant capsules	0403040Y0BBAAAA	34	£1,277
Duciltia 30mg gastro-resistant capsules	0403040Y0BCAAAA	11	£269
Duciltia 60mg gastro-resistant capsules	0403040Y0BCAAAB	10	£471

Source: NHSBSA Prescription Cost Analysis · to April 2026 OGL v3.0

Where Duloxetine hydrochloride is dispensed

The regions and dispensing practices with the highest Duloxetine hydrochloride volumes.

Top regions

NHS North East and North Cumbria Integrated Care Board 62,092
NHS West Yorkshire Integrated Care Board 33,201
NHS Greater Manchester Integrated Care Board 29,389
NHS Cheshire and Merseyside Integrated Care Board 27,215
NHS South Yorkshire Integrated Care Board 17,627

Top dispensing practices

Regional volumes from NHSBSA Prescription Cost Analysis; practice volumes from NHS dispensing data.

Compare Duloxetine hydrochloride with

Other medicines in the same BNF section, by prescribing volume.

Duloxetine hydrochloride vs Sertraline hydrochloride Duloxetine hydrochloride vs Amitriptyline hydrochloride Duloxetine hydrochloride vs Mirtazapine Duloxetine hydrochloride vs Citalopram hydrobromide Duloxetine hydrochloride vs Fluoxetine hydrochloride