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Independent analysis of NHS open data
PharmaInsight

Duloxetine hydrochloride

Central Nervous System Antidepressant drugs BNF 0403040Y0
Data updated May 2026 Download CSV

Duloxetine hydrochloride was ranked 51st of 1,796 medicines by items in May 2026, with 447,879 items, up 7.1% on a year earlier.

447,879items +7.1%

Dispensed in May 2026

4,387,786items

Rolling 12 months

£1,479,396

Net ingredient cost · May 2026

Figure 1. Duloxetine hydrochloride: national items dispensed by month

0 237k 474k Jan 2021 Nov 2021 Sep 2022 Jul 2023 May 2024 Mar 2025 Jul 2026 241,783 Jan 2021: 251k Feb 2021: 240k Mar 2021: 269k Apr 2021: 263k May 2021: 253k Jun 2021: 271k Jul 2021: 273k Aug 2021: 264k Sep 2021: 277k Oct 2021: 268k Nov 2021: 278k Dec 2021: 293k Jan 2022: 278k Feb 2022: 262k Mar 2022: 298k Apr 2022: 282k May 2022: 295k Jun 2022: 288k Jul 2022: 289k Aug 2022: 299k Sep 2022: 299k Oct 2022: 297k Nov 2022: 308k Dec 2022: 307k Jan 2023: 309k Feb 2023: 286k Mar 2023: 330k Apr 2023: 297k May 2023: 321k Jun 2023: 330k Jul 2023: 323k Aug 2023: 334k Sep 2023: 330k Oct 2023: 337k Nov 2023: 346k Dec 2023: 345k Jan 2024: 357k Feb 2024: 340k Mar 2024: 348k Apr 2024: 363k May 2024: 375k Jun 2024: 353k Jul 2024: 389k Aug 2024: 377k Sep 2024: 372k Oct 2024: 398k Nov 2024: 382k Dec 2024: 396k Jan 2025: 409k Feb 2025: 369k Mar 2025: 396k Apr 2025: 401k May 2025: 418k Jun 2025: 410k Jul 2025: 438k Aug 2025: 407k Sep 2025: 431k Oct 2025: 448k Nov 2025: 415k Dec 2025: 461k Jan 2026: 447k Feb 2026: 415k Mar 2026: 461k Apr 2026: 455k May 2026: 448k Jun 2026: 474k Jul 2026: 242k

Source: NHSBSA Prescription Cost Analysis, to May 2026

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At a glance

  • Therapeutic class Antidepressant drugs
  • Presentations 10 shown
  • Average cost / item £3.30
  • Year on year Up 7.1% on a year earlier
What this is
Net ingredient cost is the list price before discounts and dispensing fees, not what the NHS finally pays.

Top presentations, May 2026

The individual products dispensed under Duloxetine hydrochloride this month.

Presentations of Duloxetine hydrochloride, May 2026
Presentation BNF code Items Net ingredient cost
Duloxetine 60mg gastro-resistant capsules 0403040Y0AAABAB 260,137 £563,655
Duloxetine 30mg gastro-resistant capsules 0403040Y0AAAAAA 169,590 £310,315
Duloxetine 90mg gastro-resistant capsules 0403040Y0AAACAC 11,960 £387,822
Duloxetine 120mg gastro-resistant capsules 0403040Y0AAADAD 5,686 £210,531
Depalta 60mg gastro-resistant capsules 0403040Y0BDABAB 246 £1,153
Depalta 30mg gastro-resistant capsules 0403040Y0BDAAAA 110 £426
Cymbalta 60mg gastro-resistant capsules 0403040Y0BBABAB 90 £3,236
Cymbalta 30mg gastro-resistant capsules 0403040Y0BBAAAA 25 £1,020
Duciltia 30mg gastro-resistant capsules 0403040Y0BCAAAA 23 £683
Duciltia 60mg gastro-resistant capsules 0403040Y0BCAAAB 12 £554

Source: NHSBSA Prescription Cost Analysis · to May 2026 OGL v3.0

Where Duloxetine hydrochloride is dispensed

The regions and dispensing practices with the highest Duloxetine hydrochloride volumes.

Regional volumes from NHSBSA Prescription Cost Analysis; practice volumes from NHS dispensing data.

Compare Duloxetine hydrochloride with

Other medicines in the same BNF section, by prescribing volume.

Download this data

The monthly series for Duloxetine hydrochloride is in this page's CSV. For the ranked national series across every medicine, with the method and caveats documented, see the most-prescribed medicines dataset in our open data catalogue.