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Diclofenac sodium vs Methotrexate

National NHS prescribing compared (Prescription Cost Analysis)
Data updated March 2026

Methotrexate was dispensed 6.3× as often as Diclofenac sodium in March 2026 — 190,005 items versus 30,051 in England.

30,051items

Diclofenac sodium · March 2026

NHSBSA Prescription Cost Analysis

190,005items

Methotrexate · March 2026

NHSBSA Prescription Cost Analysis

Figure 1. Diclofenac sodium versus Methotrexate: national items dispensed by month

▬ Diclofenac sodium   ·   ╌ Methotrexate

Methotrexate 30,051

Source: NHSBSA Prescription Cost Analysis, to March 2026

Diclofenac sodium versus Methotrexate, March 2026
Measure Diclofenac sodium Methotrexate
Items, March 2026 30,051 190,005
Items, last 12 months 360,365 2,236,642
Net ingredient cost, March 2026 £237,800 £2,295,534

See the full profile for Diclofenac sodium or Methotrexate.