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Independent analysis of NHS open data
PharmaInsight

November 2025 in numbers

NHS community prescribing in England (Prescription Cost Analysis).
Data updated November 2025
105,006,244items

Dispensed in November 2025

NHSBSA Prescription Cost Analysis

£956,913,659

Net ingredient cost, November 2025

NHSBSA PCA

Figure 1. The most-dispensed medicines in England, November 2025

The most-dispensed medicines in England, November 202502.5m5m7.5m10mAtorvastatinLansoprazoleOmeprazoleInfluenzaMetformin hydroch…

Source: NHSBSA English Prescribing Dataset

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Most-dispensed medicines

Download full month (CSV)
Top medicines by items, November 2025
MedicineItemsNet ingredient cost
Atorvastatin 6,242,528 £5,742,239
Amlodipine 3,277,097 £2,828,722
Lansoprazole 3,021,852 £3,394,264
Ramipril 2,892,682 £2,795,060
Omeprazole 2,810,058 £7,845,145
Levothyroxine sodium 2,786,970 £3,368,415
Influenza 2,503,378 £42,474,617
Bisoprolol fumarate 2,496,518 £1,949,076
Colecalciferol 2,342,243 £9,775,959
Metformin hydrochloride 2,186,796 £5,403,897
Sertraline hydrochloride 2,065,551 £3,774,469
Aspirin 1,611,158 £1,181,227

Biggest risers

Largest month-on-month rise in items (medicines above 10,000 items).

Biggest risers month on month
MedicineItemsChange
Phenazone/lidocaine 14,114 +18.6%
Erythromycin ethylsuccinate 11,636 +10.9%
Other individually formulated bought in preparations 19,522 +8.2%
Phenoxymethylpenicillin (Penicillin V) 257,487 +4.6%
Daridorexant 17,986 +3.5%
Levonorgestrel 12,230 +3.1%
Dexamethasone 21,476 +2.9%
Benzydamine hydrochloride 55,840 +2.3%

Biggest fallers

Largest month-on-month fall in items.

Biggest fallers month on month
MedicineItemsChange
Influenza 2,503,378 −70.8%
Norethisterone 19,594 −24.6%
Fluorouracil (Sunscreen) 15,988 −17.6%
Nystatin 56,884 −15.8%
Adrenaline 28,465 −14.7%
Medroxyprogesterone acetate 18,320 −14.0%
Stockinette 30,182 −13.5%
Wound Management & Other Dressings 270,739 −13.0%

Download this data

Every medicine dispensed in November 2025 is in this month's CSV. For the full monthly history — the national headline series, and the top 500 medicines ranked in every month — see the headline series and most-prescribed medicines datasets in our open data catalogue.