October 2025 in numbers
Dispensed in October 2025
NHSBSA Prescription Cost Analysis
Net ingredient cost, October 2025
NHSBSA PCA
Figure 1. The most-dispensed medicines in England, October 2025
Source: NHSBSA English Prescribing Dataset
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Most-dispensed medicines
Download full month (CSV)| Medicine | Items | Net ingredient cost |
|---|---|---|
| Influenza | 8,584,529 | £147,831,244 |
| Atorvastatin | 6,752,807 | £6,175,947 |
| Amlodipine | 3,540,050 | £3,043,265 |
| Lansoprazole | 3,283,848 | £3,672,465 |
| Ramipril | 3,132,663 | £3,031,234 |
| Omeprazole | 3,073,258 | £8,509,526 |
| Levothyroxine sodium | 3,017,153 | £3,634,232 |
| Bisoprolol fumarate | 2,702,976 | £2,097,182 |
| Colecalciferol | 2,514,997 | £10,341,778 |
| Metformin hydrochloride | 2,368,734 | £5,879,547 |
| Sertraline hydrochloride | 2,225,316 | £3,924,706 |
| Aspirin | 1,749,303 | £1,285,671 |
Biggest risers
Largest month-on-month rise in items (medicines above 10,000 items).
| Medicine | Items | Change |
|---|---|---|
| Influenza | 8,584,529 | +11,181.6% |
| Amoxicillin | 762,388 | +32.6% |
| Doxycycline hyclate | 359,231 | +29.9% |
| Fluorouracil (Sunscreen) | 19,397 | +21.4% |
| Phenoxymethylpenicillin (Penicillin V) | 246,167 | +19.3% |
| Clarithromycin | 162,723 | +17.7% |
| Benzydamine hydrochloride | 54,581 | +17.2% |
| Mometasone furoate | 76,611 | +15.6% |
Biggest fallers
Largest month-on-month fall in items.
| Medicine | Items | Change |
|---|---|---|
| Adrenaline | 33,360 | −35.6% |
| Potassium chloride | 11,692 | −14.1% |
| Other individually formulated bought in preparations | 18,040 | −9.3% |
| Sodium cromoglicate | 40,730 | −7.9% |
| Ibandronic acid | 11,789 | −6.2% |
| Diclofenac sodium | 13,673 | −5.3% |
| Flucloxacillin sodium | 334,134 | −4.9% |
| Norethisterone | 25,998 | −4.5% |
Download this data
Every medicine dispensed in October 2025 is in this month's CSV. For the full monthly history — the national headline series, and the top 500 medicines ranked in every month — see the headline series and most-prescribed medicines datasets in our open data catalogue.