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Independent analysis of NHS open data
PharmaInsight

September 2025 in numbers

NHS community prescribing in England (Prescription Cost Analysis).
Data updated September 2025
107,711,669items

Dispensed in September 2025

NHSBSA Prescription Cost Analysis

£991,596,122

Net ingredient cost, September 2025

NHSBSA PCA

Most-dispensed medicines

Download full month (CSV)
Top medicines by items, September 2025
MedicineItemsNet ingredient cost
Atorvastatin 6,543,311 £6,131,141
Amlodipine 3,432,685 £3,017,132
Lansoprazole 3,195,881 £3,704,076
Ramipril 3,043,038 £3,116,820
Omeprazole 3,018,435 £8,438,997
Levothyroxine sodium 2,950,407 £3,797,658
Bisoprolol fumarate 2,627,696 £2,078,812
Colecalciferol 2,429,513 £9,938,355
Metformin hydrochloride 2,311,492 £6,498,367
Sertraline hydrochloride 2,165,067 £4,051,674
Aspirin 1,706,268 £1,438,410
Amitriptyline hydrochloride 1,390,794 £1,604,004

Biggest risers

Largest month-on-month rise in items (medicines above 10,000 items).

Biggest risers month on month
MedicineItemsChange
Tirzepatide 287,758 +40.4%
Influenza 76,093 +29.3%
Amoxicillin 574,941 +25.8%
Dexamethasone 18,423 +22.5%
Permethrin 23,856 +22.1%
Benzydamine hydrochloride 46,569 +21.5%
Daridorexant 15,132 +20.7%
Doxycycline hyclate 276,604 +18.9%

Biggest fallers

Largest month-on-month fall in items.

Biggest fallers month on month
MedicineItemsChange
Norethisterone 27,212 −22.0%
Potassium chloride 13,613 −18.2%
Fluorouracil (Sunscreen) 15,975 −11.0%
Sodium cromoglicate 44,217 −9.2%
Mometasone furoate 66,256 −6.3%
Flucloxacillin sodium 351,508 −5.3%
Dexamethasone 87,535 −5.0%
Ibandronic acid 12,567 −5.0%